Bibliography: Intestinal infection and stomach-acid blocker drugs links

Scientific Journal Articles

Lewis SJ, et al. Altered Bowel Function and Duodenal Bacterial Overgrowth in Patients Treated with Omeprazole (PPI). Aliment Pharmacol Ther 1996 Aug; 10(4):557-561.

Naunton M, et al. Overuse of proton pump inhibitors. J Clin Phrm Ther, 2000 October; 25 (5), 333-340.

Nardino RJ, et al. Overuse of acid suppressive therapy in hospitalized patients. Am J Gastroenterology, 2000 November; 95 (11), 3118–3122.

Sanduleanu S, Jonkers D, et al. Double gastric infection with Helicobacter pylori and non- Helicobacter pylori bacteria during acid-suppressive therapy: increase of pro-inflammatory cytokines and development of atrophic gastritis. Aliment Pharmacol Ther 2001 Aug; 15(8):1163-75.

Cunningham R, et al. Proton pump inhibitors as a risk factor for Clostridium difficile diarrhea. J Hosp Infect. 2003 Jul;54(3):243-5.

Dial S, Alrasadi K, et al. Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies. CMAJ.2004 Jul;171(1):33-8.

Wang K, Lin HJ, et al. The Effect of H2-receptor antagonist and proton pump inhibitor on microbial proliferation in the stomach. Hepatogastroenterology 2004 Sep-Oct; 51(59):1540-3

Martinsen T, et al. Gastric Juice: A Barrier Against Infectious Disease. Basic & Clinical Pharmacology & Toxicology. 2005; 96 (2), 94–102.

Al-Tureihi FI, et al. Albumin, length of stay, and proton pump inhibitors: key factors in Clostridium difficile-associated disease in nursing home patients. J Am Med Dir Assoc. 2005 Mar-Apr;6(2):105-8.

Dial S, Delaney JAC, et al. Use of Gastric Acid-Suppressive Agents and the Risk of Community-Acquired Clostridum difficile-Associated Disease. JAMA 2005 Dec 21; Vol 294, No. 23.

Stiefel U., Jump L.P. ,and Donskey C.J. Suppression of gastric acid production by proton pump inhibitor treatment facilitates colonization of the large intestine by vancomycin-resistant Enterococcus and Klebsiella pneumoniae in clindamycin-treated mice (Abstract B-1123). 46th Interscience Conference on Antimicrobial Agents and Chemotherapy. Sept. 27-30, 2006. San Francisco.

Dial S, Delaney JAC, et al. Proton pump inhibitor use and risk of community acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy. CMAJ 2006 Sep 26; 175(7), 745-48.

Cunningham R. Proton pump inhibitors and the risk of Clostridium difficile-associated disease: further evidence from the community. CMAJ 2006 Sep 26; 175(7), 757-58.

Canani RB, et al. Therapy with gastric acidity inhibitors increase the risk of acute gastroenteritis and community-acquired pneumonia in children. Pediatrics. 2006 May;117(5):e817-20.

Guillet R, Stoll B, et al. Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in Very Low Birth Weight Infants Pediatrics. 2006;117:e137-e142 (doi:10.1542/peds.2005-1543).

Patole S. Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis: a case of excessive collateral damage? Pediatrics. 2006;117:531-532 (doi:10.1542/peds.2005-2230).

Dasgupta R. Proton Pump Inhibitor Use by Hospital Inpatients as a Risk for Nosocomial Infection by Clostridum Difficile. MMJ. Vol.III, No. 3; July 2006.

Yearsley KA, et al. Proton pump inhibitor therapy is a risk factor for Clostridium-difficile-associated diarrhea. Aliment Pharmacol Ther 2006 Aug 15; 24(4):613-19.

Jensen R.T. Consequences of Long-Term Proton Pump Blockade: Insights from Studies of Patients with Gastrinomas. Basic & Clinical Pharmacology & Toxicology. 2006; 98 (1), 4–19.

Popular Press - News releases:

Heartburn, Ulcer Drugs linked to Rise of Infections (Update1). Bloomberg.com, Dec 19, 2005

Heartburn Drugs Cause Diarrhea? CBS News, Dec 20, 2005.

Common Reflux Treatment Linked to Life Threatening Bowel Infection in Premature Infants. NIH News. Feb 8, 2006. http:// www.nichd.nih.gov/news/releases/common_reflux.cfm

Article Review from www.medpage today - Feb 9 06: H2 Blockers in Preemies Raise Necrotizing Enterocolitis Risk

Flora Horror: Hospitals Struggle with a Serious New Gut Microbe. Science News. Feb. 18, 2006; 169: 7

Prescribing: Stressing appropriate stress ulcer prophylaxis. Shands at the Univ. of Florida Drug & Therapy Bulletin. March 2006.

Do Acid Blockers Let Microbes Reach the Colon? Science News. Oct 21, 2006;170: 269

Heartburn drugs are blamed for superbug that kills thousands. Daily Mail. March 13, 2007.